49ers Edge Cardinals 16-15 with Last-Second Field Goal, Maintain Undefeated Start

The San Francisco 49ers secured a narrow 16-15 victory over the division-rival Arizona Cardinals on Sunday, September 21, 2025, at Levi's® Stadium. The hard-fought win, clinched by a last-second field goal, propelled the 49ers to a 3-0 start to their season, despite what one fan described as an "ugly" contest. The game was marked by significant injuries and a dramatic fourth quarter.

The decisive play came from newly signed kicker Eddy Pineiro, who drilled a 35-yard field goal as time expired. Pineiro's heroics capped a late-game drive led by backup quarterback Mac Jones, who was pressed into service due to starting quarterback Brock Purdy's absence. Jones, who moved the 49ers 59 yards in the final 1:46, expressed his determination, stating, "I just knew the guys had my back and like we talked about on the sidelines, go out there and rip it."

The game was a physical battle, with both teams struggling offensively for much of the contest. The 49ers faced adversity early when star defensive end Nick Bosa left the game in the first quarter with a knee injury, though initial tests did not indicate a torn ACL. The Cardinals took a late 15-13 lead after a safety, setting the stage for San Francisco's final drive.

The sentiment among the fanbase reflected the challenging nature of the win. As tweeted by "T Wolf 🌁," > "These are the wins that build champions. Everyone is hurt. Division rival. Ugly. But a win is a win! @49ers." This perspective highlights the gritty determination of the team to overcome obstacles and maintain their perfect record.

With this victory, the 49ers improve to 3-0, positioning themselves strongly in the NFC West. They are set to host the Jacksonville Jaguars in Week 4, looking to continue their undefeated run despite the early-season injuries and close calls.