Altman Suggests OpenAI Could Soon Be Led by an AI CEO

San Francisco, CA – Sam Altman, CEO of OpenAI, has publicly stated his belief that an artificial intelligence could eventually lead the company, remarking, "Shame on me if OpenAI is not the first big company run by an AI CEO." The comment was made during a conversation with economist Tyler Cowen, recorded live at the Progress Conference 2025. Altman's statement underscores his long-held view that AI systems could surpass human capabilities even in top leadership roles.

Altman has previously expressed enthusiasm for the prospect of AI leadership, noting in an October 2025 interview that he expects AI systems to be capable of running OpenAI better than he can. He stated, "I think there will come a time when AI can be a much better CEO of OpenAI than me – and I will be nothing but enthusiastic the day that happens." This sentiment reflects a broader vision for AI's transformative potential across all sectors.

The OpenAI CEO's remarks come amidst the company's aggressive expansion and significant investment in AI infrastructure, including plans to commit $1.4 trillion to developing computing resources. While OpenAI reported over $13 billion in annual revenue, it continues to operate at a loss due to these massive expenditures, which Altman defends as a "forward bet" on achieving artificial general intelligence (AGI). The company's valuation has surged, with a secondary sale valuing it at approximately $500 billion earlier this year.

Altman's predictions extend beyond executive leadership, as he also anticipates AI agents will "join the workforce" and materially change company output in 2025. He has suggested that AI could replace 40% of tasks across various jobs, with customer support being a prime example of a role that could be "totally, totally gone." Despite these disruptions, Altman maintains an optimistic outlook, believing human ingenuity will adapt and create new opportunities.

The discussion at the Progress Conference highlights the ongoing debate about AI's role in society and the future of work. Altman's vision for an AI-led company, while ambitious, aligns with OpenAI's mission to advance AI in a way that benefits all of humanity, even if it means redefining traditional leadership structures.