Artbio

Overview

ARTBIO is a clinical-stage radiopharmaceutical biotechnology company focused on developing a pioneering category of alpha radioligand therapies (ARTs). Founded in 2021 in Cambridge, MA, it was established on the scientific foundations laid by founders Roy Larsen and Øyvind Bruland, aligned with Radforsk and F-Prime Capital. ARTBIO's aim is to redefine cancer treatment through alpha radioligand therapy, employing technologies such as their proprietary AlphaDirect™. The company has successfully raised significant funds, including $90 million in a Series A round and $132 million in a Series B round, indicating strong investor confidence.

Recent Developments

  • July 2025: ARTBIO announced a $132 million Series B funding round aimed at advancing its pipeline, including the development of its lead program, AB001 for metastatic castration-resistant prostate cancer, and expanding its manufacturing and supply chain infrastructure. The funding was led by Sofinnova Investments and B Capital, with contributions from existing investors F-Prime Capital and Omega Funds.
  • December 2023: ARTBIO raised $90 million in a Series A funding round to progress its pipeline and technology development for alpha radioligand therapies. This funding was critical at the time due to the challenging financial environment.
  • November 2024: ARTBIO entered into a licensing and research partnership with 3B Pharmaceuticals to advance a novel alpha radioligand therapy for solid tumor treatments.
  • Early 2023: The company appointed Emanuele Ostuni as CEO, marking a strategic move to bolster its leadership and advance its proprietary technology.
  • ARTBIO's innovative AlphaDirect™ technology, a Pb212 isolation method, enables a distributed manufacturing approach for ARTs. This method enhances their potential for efficacy and safety, spearheading ARTBIO's mission in nuclear medicine advancement.

Company Information

AttributeInformation
Founding Date2021
HeadquartersCambridge, MA
FoundersRoy Larsen, Øyvind Bruland
RevenueNot publicly disclosed
ProfitsNot publicly disclosed
Key InvestorsSofinnova Investments, B Capital, F-Prime Capital, Omega Funds
IndustryRadiopharmaceuticals
Number of Employees68

Early History

ARTBIO was born out of groundbreaking research by the illustrious University of Oslo and Norway's Radium Hospital. Its co-founders, Roy Larsen and Øyvind Bruland, have had a remarkable journey in radiology and radiation therapy, having been instrumental in the creation of Xofigo, the first metabolically targeted alpha therapy later acquired by Bayer. ARTBIO was established in 2021, grounded in this rich scientific tradition. The company's vision was to innovate cancer treatment by developing alpha radioligand therapies, an uncharted frontier in nuclear medicine. With initial seed funding of $23 million, ARTBIO embarked on its journey to create a robust ecosystem catering to the unique demands of ART production and distribution.

Company Profile and Achievements

ARTBIO's business model revolves around leveraging its proprietary AlphaDirect™ technology to develop ARTs that combine the optimal alpha-emitting isotope, Pb212, with tumor-specific targets. This approach is characteristic of the company’s commitment to creating highly effective and safe cancer treatments. Notable achievements include:

  • Product Development: Launch of pipeline programs, with AB001 currently in first-in-human trials.
  • Funding Milestones: Achieving considerable financial backing through Series A and B funding, revealing robust investor trust.
  • Technological Advancement: Development of AlphaDirect™, a ground-breaking Pb212 isolation method, revolutionizing ART manufacturing and distribution.
  • Strategic Partnerships: Partnership with 3B Pharmaceuticals to conduct expansive research on pioneering ARTs for solid tumors.

Current Operations and Market Position

Currently, ARTBIO is advancing multiple ART programs targeted at cancers with high unmet medical needs. The company is deeply integrated into the oncology market, focusing on developing standard care alternatives in nuclear medicine. ARTBIO's AlphaDirect™ offers competitive advantages by facilitating a scalable and reliable manufacturing process for ARTs, addressing significant production and delivery challenges in the industry. Leveraging these capabilities, ARTBIO is well-positioned to establish itself as a leader in the radiopharmaceutical landscape.

Conclusion

ARTBIO stands at the forefront of redefining cancer care through its innovative alpha radioligand therapies. With a robust pipeline, backed by significant Series A and B funding, and a strategic vision supported by cutting-edge technology, ARTBIO is poised to influence the future of oncology significantly. As the company continues to expand its manufacturing capabilities and advance its clinical trials, it holds substantial potential to create new treatment paradigms in nuclear medicine, offering hope for more effective and safer cancer therapies.

References

  1. Artbio Official Website
  2. LinkedIn - Artbio
  3. Crunchbase - Artbio
  4. Pitchbook - Artbio
  5. PR Newswire
  6. FierceBiotech
  7. GeneOnline
  8. PR Newswire - Funding
  9. Finsmes
  10. PR Newswire - Partnership