Daniel Nadler (OpenEvidence)

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Overview

Daniel Nadler is a Canadian-born technology entrepreneur, best known for being the co-founder and CEO of OpenEvidence, an AI-powered medical search engine tailored for clinicians. An acclaimed figure in the tech industry, Nadler was listed on TIME100 Health 2025 for his considerable influence in global health. He has a diverse academic background, having completed a Ph.D. from Harvard University focusing on the pricing mechanisms of credit derivatives. He is also widely recognized for his previous venture, Kensho Technologies, which revolutionized financial analytics and was sold to S&P Global for $550 million.

Recent Developments

  • July 2025: OpenEvidence raised $210 million in a Series B funding round, which elevated the company's valuation to $3.5 billion. The funding round was co-led by GV (Google Ventures) and Kleiner Perkins.
  • 2025: Daniel Nadler was named to the TIME100 Health list, highlighting his contributions to medical advancements through AI.
  • April 2025: A strategic partnership was established between OpenEvidence and the New England Journal of Medicine, allowing OpenEvidence to use all its findings since 1990.
  • 2024-2025: OpenEvidence experienced a significant increase in its platform usage. By July 2025, the software was supporting 8.5 million monthly consultations and was used by over 40% of U.S. physicians.
  • March 2025: OpenEvidence introduced "DeepConsult," a new AI agent for physicians, offering advanced research capabilities for complex clinical inquiries.

Personal Information

AttributeInformation
Full NameDaniel Joseph Nadler
BornToronto, Ontario, Canada
NationalityCanadian
OccupationEntrepreneur, Poet, and Executive
Known ForFounder of OpenEvidence and Kensho Technologies
Net WorthEstimated at $2.3 billion as of 2025
EducationPh.D. in Financial Modeling from Harvard University

Early Life and Education

Daniel Nadler was born in Toronto, Ontario, where his family originally hailed from Poland and Romania. His father, an engineer, played a critical role in his early education, teaching him "real math," which laid the foundation for his academic pursuits. Nadler attended Harvard University, where he studied mathematics and classics, and also engaged in creative experiences, studying poetry under Pulitzer Prize-winning poet Jorie Graham. During his academic career, he was a visiting scholar at the Federal Reserve, where he authored a Ph.D. thesis addressing econometric and statistical approaches in financial modeling.

Career and Notable Achievements

Daniel Nadler's professional journey took a significant turn when he co-founded Kensho Technologies in 2013. Kensho aimed to democratize financial analysis through AI, eventually attracting attention for its innovative approach to data handling:

  • Kensho's major achievement came in 2018 when it was acquired by S&P Global for $550 million, making it one of the decade's largest AI deals.
  • In 2021, building on his desire to solve critical real-world problems, Nadler co-founded OpenEvidence alongside co-founder Zachary Ziegler to tackle information overload in medicine through AI.
  • OpenEvidence gained rapid traction due to its free-for-doctors model, leading to its widespread adoption among clinicians.

Current Work and Impact

Currently, Daniel Nadler actively leads OpenEvidence, driving innovation in the field of medical research and AI-assisted decision-making for clinicians. By aligning global medical knowledge, OpenEvidence facilitates quicker and more informed medical decisions, offering critical support at the point of care. Nadler's entrepreneurial ventures have cemented his legacy as a profound influencer reshaping the intersection of technology and healthcare.

Personal Influences

Daniel Nadler's creative pursuits extend beyond technology. He published a poetry collection, "Lacunae: 100 Imagined Ancient Love Poems," which NPR honored as a 'Best Book of the Year' in 2016. His artistic inclinations also led him to co-finance and produce films like "Motherless Brooklyn" and "Palmer," underscoring his versatile talent across different domains.

What Is Open Evidence AI

OpenEvidence is an AI-enhanced medical search engine, focused on integrating vast quantities of peer-reviewed literature for clinical inquiries. It provides real-time, evidence-based recommendations, fundamentally enhancing the clinical decision-making process by being rooted in reliable medical sources, including strategic agreements with entities like the New England Journal of Medicine.

Daniel Nadler Net Worth

As of 2025, Daniel Nadler's net worth is estimated to be $2.3 billion. This financial milestone is attributable to his substantial ownership stake of approximately 60% in OpenEvidence, alongside the financial success of Kensho Technologies.

Conclusion

Daniel Nadler's contribution to technology and medicine has positioned him as a key visionary in AI integration for healthcare. His efforts through OpenEvidence continue to empower physicians by bridging the knowledge gap and aiding informed medical practices. As AI and health technologies evolve, Nadler's role will likely remain pivotal, reinforcing his legacy as a transformative figure in the global medical landscape.

References

  1. Forbes Article on OpenEvidence
  2. OpenEvidence Official Site
  3. TIME100 Health - Daniel Nadler
  4. American Bazaar Online
  5. The Guardian on Developments
  6. OpenEvidence company details on LinkedIn
  7. PRNewswire Press Release
  8. AI Magazine on OpenEvidence
  9. Medical Buyer on OpenEvidence
  10. Forbes Profile