Shawn Lockery, Ph.D. (InVivo Biosystems): 10 Key Things You Must Know
Overview
Shawn Lockery, Ph.D., is a prominent neuroscientist and entrepreneur, renowned for his pioneering work in microfluidics and neurophysiology. As a co-founder and the Chief Technology Officer of InVivo Biosystems, Lockery's contributions to the field of biotechnology have been significant, particularly in the development of innovative platforms for drug discovery. InVivo Biosystems leverages genome editing and electrophysiological techniques to accelerate research in disease modeling using organisms like C. elegans and zebrafish. This article delves into ten key aspects of Lockery's career and achievements, highlighting the breadth and impact of his work.
1. Early Life and Education
Shawn Lockery's academic journey began with a Bachelor of Arts in Philosophy and Psychology from Yale University. He later pursued a Ph.D. in Neuroscience at the University of California, San Diego, where he was a Wellcome Trust Scholar. His fascination with the intricacies of biology and technology has underpinned his career, leading him to delve into the realms of computational neuroscience and electrophysiology.
2. Academic Career
Lockery has served as a Professor of Neuroscience at the University of Oregon. His research there focuses on understanding the neural and genetic bases of behavior, particularly using the model organism C. elegans. This work has contributed to a greater understanding of cognitive functions and disorders, with implications for developing potential therapeutic strategies.
3. Co-Founder of NemaMetrix
In 2011, Shawn Lockery co-founded NemaMetrix, which later evolved into InVivo Biosystems. The company initially focused on creating microfluidic systems for measuring nematode health, applying Lockery's expertise in neurophysiology and microfluidics. The success of these platforms underscored Lockery's role as a leader in innovative biotechnology solutions.
4. Contributions to InVivo Biosystems
At InVivo Biosystems, Lockery has been instrumental in the development and commercialization of genome editing technologies, including CRISPR. Under his leadership, the company has expanded its capabilities to provide services that aid pharmaceutical and biotechnology companies in drug discovery and development through custom edited models and phenotypic assays.
5. ScreenChip Technology
One of Lockery’s significant inventions is the ScreenChip system, a groundbreaking platform recognized by the White House as one of life science’s breakthrough technologies. It has been pivotal in enabling high-throughput screening of drug effects on nematode models, thereby expediting early-stage pharmaceutical research.
6. Role in Disease Modeling
Lockery’s work has facilitated advances in modeling rare diseases, particularly using C. elegans and zebrafish. By creating genetically engineered models, his work allows for detailed studies of disease mechanisms, contributing to the identification of potential therapeutic targets for conditions where treatments are scarce.
7. Executive Leadership at InVivo Biosystems
As Chief Technology Officer, Lockery has guided the strategic development of InVivo Biosystems, integrating CRISPR technology and expanding the company’s services in drug testing and disease modeling. His leadership continues to drive the company's growth and innovation in the biotech sector.
8. Membership on Boards
Lockery is an active member of several boards, including serving on the board of NemaMetrix, where he continues to influence the strategic directions of organizations at the forefront of biotechnology innovation. His insights from academic and entrepreneurial perspectives are highly valued.
9. Impact on Biotechnology Industry
Lockery's contributions have had a significant impact on the biotechnology industry, particularly in the realm of genetic and disease research. By advancing tools and methodologies, his work supports not only commercial enterprises but also academic research groups aiming to unlock new therapies.
10. Future Prospects
With ongoing developments at InVivo Biosystems, Lockery is poised to continue influencing the field of biotechnology. The expansion into areas like central nervous system diseases and advanced therapeutic models signals a future rich with potential breakthroughs, reinforcing his reputation as a visionary in life sciences.
Conclusion
Shawn Lockery's career embodies a blend of academic excellence and entrepreneurial spirit, establishing him as a key figure in modern neuroscience and biotechnology. His foundational work in microfluidics and CRISPR technology has amplified the capacity for innovation within disease research and drug development. As the fields of neuroscience and biotechnology continue to evolve, Lockery's contributions serve as a testament to the power of interdisciplinary research and dedication to scientific advancement.