12 Fatalities Confirmed in Louisville UPS Plane Crash After Engine Detaches

Louisville, Kentucky – A UPS cargo plane, Flight 2976, crashed shortly after takeoff from Louisville Muhammad Ali International Airport on Tuesday, November 4, 2025, resulting in at least 12 confirmed fatalities. The National Transportation Safety Board (NTSB) is investigating the incident, which involved an engine detachment, a significant fire, and subsequent explosion. The McDonnell Douglas MD-11, bound for Honolulu, was carrying three crew members, all of whom are believed to be among the deceased, alongside nine individuals on the ground.

NTSB investigator Todd Inman confirmed that airport security video showed the plane's left engine detaching from the wing during the takeoff roll. A large plume of fire erupted around the left wing before the aircraft crashed off airport property, igniting a string of blazes and scattering debris over a half-mile radius. Investigators have since recovered the aircraft's cockpit voice recorder and flight data recorder, commonly known as "black boxes," which are crucial for determining the crash's cause.

Kentucky Governor Andy Beshear declared a state of emergency, mobilizing resources for the extensive recovery efforts. The crash impacted several structures beyond the runway, including a petroleum recycling facility that exploded. University of Louisville Health reported treating 15 patients for injuries ranging from burns to shrapnel, with two remaining in critical condition.

The incident led to a temporary shutdown of Louisville's airport and disrupted operations at UPS's Worldport facility, its global air cargo hub. While the airport has partially reopened, the runway involved in the accident is expected to remain closed for approximately 10 days. UPS CEO Carol Tomé expressed deep sadness, stating, "We have suffered a tragic accident involving Flight 2976. We are deeply saddened and our hearts continue to be with all who have been impacted."

Aviation experts noted the rarity of an engine detaching during takeoff, with some suggesting a dramatic failure of two engines may have occurred. The MD-11 was fully loaded with 38,000 gallons of jet fuel for its long journey, which likely intensified the post-crash fire. The NTSB's investigation is expected to be extensive, potentially taking 12 to 24 months to determine the probable cause and issue recommendations.