Free 2025 'BroScience Guide' on Peptides Promotes Unregulated Biohacking Practices Amidst Scientific Scrutiny

A new publication, "The BroScience Guide to Peptides (2025 Edition)," authored by Alexander Cortes, known as AJAC, is being offered as a free resource for individuals interested in biohacking and health optimization. The guide positions peptides as "the most powerful tools in modern biohacking," claiming their potential for optimizing fat loss, reversing inflammation, boosting mitochondrial function, enhancing brain performance, accelerating recovery, deepening sleep, regenerating tissue, and radically shifting body composition. According to the tweet promoting the guide, it provides a "no-BS breakdown of what peptides are, how they can work, and how real people are using them to look, feel, and perform years younger.

AJAC, a certified personal trainer, has built a following by applying scientific and clinical data to fitness, often challenging conventional wisdom under the "broscience" moniker. His latest guide aims to serve as a blueprint for those ready to "assert agency over their health and enter the biohacking world," promising "practical and actionable knowledge" from firsthand experience. The release taps into a growing interest in self-guided health optimization.

Peptides are short chains of amino acids, the building blocks of proteins, and some are legitimately used in medicine, such as insulin and certain weight-loss medications. However, many of the peptides gaining traction in biohacking circles are experimental and lack approval from regulatory bodies like the U.S. Food and Drug Administration (FDA) for human use. These substances have not undergone rigorous clinical trials to establish their safety and efficacy in humans.

Medical experts and anti-doping agencies have raised significant concerns regarding the widespread, unregulated use of these experimental peptides. Organizations like the World Anti-Doping Agency have banned several peptides, including BPC-157 and Ipamorelin, citing a lack of human safety data and potential for performance enhancement. The scientific community warns of unknown long-term risks, questionable manufacturing standards, and potential severe side effects, including allergic reactions, heart issues, and injection-related injuries.

The appeal of such substances is often fueled by anecdotal evidence and social media influencer hype, outpacing robust scientific research. While some preliminary animal studies show promise for certain peptides in areas like tissue repair, human data remains extremely limited. Experts caution that individuals experimenting with these compounds are essentially acting as test subjects in an uncontrolled environment, risking their health without a clear understanding of the full implications.